Cancer immunotherapy: current opportunities and perspectives

Cancer immunotherapy is a relatively new and promising method of treating neoplasms. Understanding the antigen-directed cytotoxicity T-lymphocytes has become one central directions in involving immune system fight against cancer. Basic research this area led to invention checkpoint inhibitors, adoptive T-cell therapy, cancer vaccines. Cytokines can enhance action for their ability directly stimulate effector stromal cells tumor focus recognition by cytotoxic cells. They were first remain relevant day. Today, an effective treatment most malignant tumors, including melanoma, non-small cell lung cancer, liver, stomach, bladder, cervical some types breast lymphoma, etc. However, tumors ineffective, therefore, development improvement existing agents actively underway, there hope that indications its use will expand. For purpose, review discusses principles various classes immunotherapeutic anticancer agents, namely cytokines, adaptive therapy. The work highlights indications, efficacy toxicity from each class drugs, as well prospects drugs.